About Recombinant Human Syndecan-1/SDC1/CD138 Protein(C-6His)

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BackgroundSyndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Stability and StorageLyophilized protein should be stored at <-20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at <-20℃ for 3 months
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Endotoxin<1.0 EU per µg as determined by LAL test.
Purity>95% as determined by reducing SDS-PAGE.
SynonymSyndecan-1; SYND1; CD138; SDC1; SDC
SourceRecombinants or rec. proteins
Expressed HostHuman cells
Mol Mass24.7 kDa
AP Mol Mass47 kDa
Fusion tagC-6His