The best quality, top Anti - SDCBP Antibody, Anti - Syndecan 4 (SDC4) Antibody, Recombinant Human Syndecan - 4 products prices, the best delivery.
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|Description||Syndecan-2, also known as SYND2, HSPG1, HSPG, and Fibroglycan, is a protein that in humans is encoded by the SDC2 gene. The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. By Southern hybridization to a panel of human-mouse somatic cell hybrid DNA and by in situ hybridization, Marynen et al.(1989) showed that the heparan sulfate proteoglycan core protein maps to 8q22-q24.(Heparan sulfate proteoglycan of basement membrane appears to be encoded by a gene on human chromosome 1.Bobardt et al.(2003) demonstrated that syndecans, including SDC2, can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparan sulfate chains. Flow cytometric analysis demonstrated SDC expression on endothelial cells. HIV bound to SDC on endothelial cell lines maintained its infectivity for at least 1 week, compared with less than 1 day for unbound virus. Bobardt et al.(2003) suggested that SDC-rich endothelial cells lining the vasculature can provide a microenvironment that boosts HIV replication in T cells.|
|Storage||After reconstitution, the Syndecan 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.|
|Notes||The stated application concentrations are suggested starting amounts. Titration of the Syndecan 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.|
|Species reactivity||Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.|
|Immunogen||An amino acid sequence from the middle region of human Syndecan 2/HSPG (EETDKEKVHLSDSERKMD) was used as the immunogen for this Syndecan 2 antibody.|
|Properties||If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.|
|Intented use||This Syndecan 2 antibodyis to be used only for research purposes and not for diagnostics..|
|Recommended dilutions||Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml|
|Concentration||0.5mg/ml if reconstituted with 0.2ml sterile DI water|
|Host animal||Rabbit (Oryctolagus cuniculus)|
|Clonality||Polyclonal (rabbit origin)|
|Form||Antigen affinity purified|
|Recognised antigen||Syndecan 2 (HSPG)|
|Tested applications||WB, IHC-P, IHC-F|