About Syndecan-1 Antibody / CD138

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DescriptionSyndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
StorageAfter reconstitution, the SDC1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
ImmunogenAmino acids ENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKE of human Syndecan-1 were used as the immunogen for the SDC1 antibody.
Intented useThis SDC1 antibodyis to be used only for research purposes and not for diagnostics..
NotesOptimal dilution of the SDC1 antibody should be determined by the researcher.
Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host animalRabbit (Oryctolagus cuniculus)
Recommended dilutionsWestern blot: 0.1-0.5ug/ml
ClonalityPolyclonal (rabbit origin)
FormAntigen affinity purified
ClonePolyclonal antibody
Recognised antigenSyndecan-1 / CD138
PurityAntigen affinity
French translationanticorps
Uniprot #P18827
Tested applicationsWB