About Syndecan 4 Antibody

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Detail Description
Description Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Storage After reconstitution, the Syndecan 4 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
Species reactivity Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Properties If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Immunogen Amino acids MKKKDEGSYDLGKKPIYKKAPTNEFYA of human Syndecan 4 were used as the immunogen for the Syndecan 4 antibody.
Intented use This Syndecan 4 antibodyis to be used only for research purposes and not for diagnostics..
Notes Optimal dilution of the Syndecan 4 antibody should be determined by the researcher.
Recommended dilutions Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
Concentration 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host animal Rabbit (Oryctolagus cuniculus)
Clonality Polyclonal (rabbit origin)
Form Antigen affinity purified
Clone Polyclonal antibody
Purity Antigen affinity
Conjugation Unconjugated
Recognised antigen Syndecan 4
French translation anticorps
Tested applications WB, IHC-P
Localization Membrane
Category Antibody
Uniprot # P31431