About anti- CD138/Syndecan-1 antibody

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BackgroundThe protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Image1Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01423( SDC1, CD138 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Image4Raji cells were subjected to SDS PAGE followed by western blot with FNab01423(SDC1, CD138 antibody) at dilution of 1:1000
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity≥95% as determined by SDS-PAGE
PurificationImmunogen affinity purified
Tested ApplicationELISA, WB, IHC
SpecificityHuman, Mouse
Immunogensyndecan 1
French translationanticorps
Calculated MW32 kDa
Uniprot IDP18827