About Syndecan1 Antibody

The following list shows the most important features of our product:

Size

0,1 mg

Catalog no

PB9743

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Details

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DetailDescription
BackgroundSyndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Related articles1. Ala-Kapee M, Nevanlinna H, Mali M, Jalkanen M, Schröder J (September 1990). "Localization of gene for human syndecan, an integral membrane proteoglycan and a matrix receptor, to chromosome 2". Somat. Cell Mol. Genet.16 (5): 501–5. 2. Mali M, Jaakkola P, Arvilommi AM, Jalkanen M (April 1990). "Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans". J. Biol. Chem. 265 (12): 6884–9.
Storage condtionsKeep the Syndecan1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
SynonymsCD_antigen antibody|CD138 antibody|CD138 antigen antibody|heparan sulfate proteoglycan fibroblast growth factor receptor antibody|SDC antibody|Sdc1 antibody|SDC1_HUMAN antibody|SYND1 antibody|Syndecan 1 antibody|syndecan proteoglycan 1 antibody|Syndecan-1 antibody
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan-1 (218-251aa ENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKE), different from the related mouse sequence by six amino acids, and from the related rat sequence by four amino acids.
TipsThe Syndecan1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reacts with species:rat Theoretical reactivity:human
PurificationImmunogen affinity purified.
Type of the antibodyIgG polyclonal antibody
ClonalityPolyclonal antibody
ClonePolyclonal antibody
Product formfreeze-dried
Protein NameSyndecan-1
Gene Full Namesyndecan 1
Target antigenSyndecan1
French translationanticorps
Uniprot IDP18827
Raised inrabbit
Gene NameSDC1
Entrez GeneID6382
AnalysesWB