About Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9 Protein(C-6His)

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Size

10µg

Catalog no

PKSH033095-10µg

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Details

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DetailDescription
BackgroundSyntenin-1 is a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
SynonymSyntenin-1; Melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1;Syndecan-binding protein 1; SDCBP; MDA9; SYCL;
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Stability and StorageStore at <-20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
FormulationSupplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Endotoxin<1.0 EU per µg as determined by LAL test.
Purity>95% as determined by reducing SDS-PAGE.
SourceRecombinants or rec. proteins
Grouprecombinants
SequenceSer2-Val298
Mol Mass33.5 kDa
Expressed HostE.coli
AP Mol Mass33 kDa
AccessionO00560
Fusion tagC-6His
ActivityNA