About Syndecan 3 Antibody

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DescriptionSyndecan-3, also called SYND3, is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.
StorageAfter reconstitution, the Syndecan 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
NotesThe stated application concentrations are suggested starting amounts. Titration of the Syndecan 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
ImmunogenAn amino acid sequence from the N-terminus of mouse Syndecan 3 (AQRWRNENFERPVDLE) was used as the immunogen for this Syndecan 3 antibody (100% rat homology).
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Intented useThis Syndecan 3 antibodyis to be used only for research purposes and not for diagnostics..
Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
FormAntigen affinity purified
ClonePolyclonal antibody
PurityAntigen affinity
Recognised antigenSyndecan 3
French translationanticorps
Tested applicationsWB, IHC-P
Uniprot #Q64519